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Abstract #3534

In Vivo High-Resolution T1&[rho] MRI of the Wrist at 3T: Usefulness of Realignment During Post-Processing

Hon J. Yu1, Dave Michael Hitt2, Hiroshi Yoshioka3

1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, Irvine, CA, United States; 2U.S. Clinical Science , Philips Healthcare, Cleveland, OH, United States; 3Radiological Sciences, University of California, Irvine, Orange, CA, United States

T1&[rho] scans with varying TSL were performed for T1&[rho] mapping of wrist cartilage at a 3T clinical scanner. The effect of motion correction prior to the fitting for T1&[rho] mapping was tested off-line via ROI-averaged value from the T1&[rho] maps with and without motion correction and also use of R2 map for overall fitting quality. A measurable deviation in ROI-averaged T1&[rho] value of cartilage (up to 22%) occurred even in presence of small mis-alignments in T1&[rho] series (< 1&[deg]/< 0.5 mm in rotation/translation) due to the thin anatomical nature of cartilage. Overall fitting quality improved with motion correction (R2=0.94-0.96 vs. 0.72-0.80). Mapping-based techniques for cartilage require a motion-correction/realignment for more accurate assessment of cartilage.

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Keywords

accurate alignment although anatomical apparent applicable articular artifacts assessed assessing assessment audience author axis balanced best body cartilage certainly channel classified clinical clinicians coded coefficient coil color compensating console coronal corrected correction currently curved custom damage degree degrees despite detecting deviations differ diffusion dimensionally drawn durations early easily evaluated exhibited expected fitting freedom functional generated generation green hence horizontally implementation in vivo induced joint knowledge larger light likely lock locking long manually mapping maps math measurable medical morphologic motion nature necessary occur offering orange orientation oriented overall package pixel post potential preparatory prepared previously primarily prior procedures processed processing progressively protocol pulse pulses quality quantification quantitative radiological ranging realignment relatively repair required researchers resolution respect respectively rigid role rotary rotation scanner science sciences self series slice slices software spin step still structural structure subsequent substantially symptoms systems target thin tool transformation translation usefulness utilized utilizing various varying vendor vendors vertically wrist yellow yielded