Mohan L. Jayatilake1,
Aneela Afzal1, Xin Li1, Yiyi Chen2, William
J. Woodward1, Tibor J. Kovacsovics3, William H. Fleming3,
4, Wei Huang1
1Advanced
Imaging Research Center, Oregon Health & Science University, Portland,
OR, United States; 2Biostatistics, Oregon Health & Science University,
Portland, OR, United States; 3Center for Hematologic Malignancies,
Knight Cancer Institute, Oregon Health & Science University, Portland,
OR, United States; 4Oregon Stem Cell Center, Oregon Health &
Science University, Portland, OR, United States
Nine newly diagnosed acute myelogenous leukemia (AML) patients underwent DCE-MRI of vertebral body and iliac crest before standard chemotherapy. The pre-therapy bone marrow mean kep was found to be a good predictor of complete remission following therapy. DCE-MRI may be a useful noninvasive imaging method for non-solid tumor cancer studies.