Meeting Banner
Abstract #3372

Towards the Investigation of Breast Tumor Malignancy Via Electric Conductivity Measurement

Ulrich Katscher1, Hiroyuki Abe2, Marko K. Ivancevic3, Karim Djamshidi1, Philipp Karkowski1, Gillian M. Newstead2

1Philips Research Europe, Hamburg, Germany; 2Medical Center, University of Chicago, Chicago, IL, United States; 3MR Clinical Science, Philips Healthcare, Cleveland, OH, United States

According to ex vivo studies, breast tumors exhibit a significantly altered electric conductivity. This feature opens the chance to increase the specificity of breast tumor characterization with MRI. The electric conductivity can be measured in vivo using Electric Properties Tomography (EPT). Due to the complex frayed structure of fat and ductile tissue in the breast, an EPT reconstruction algorithm dedicated for breast tissue was developed, which is applied in this study to eight breast cancer patients. The study tries to contribute to the discussion if breast tumor conductivity can be measured reliably with EPT, aiming for future tumor malignancy staging.

Keywords

according aiming altered amplitude applied around authors benign best boundary breast cancer chance channel characterization circles classified clearly clinical coil color completely complex conductivities conductivity containing contrast contribute cordially correlation dedicated derivative determine determines developed ductile eight electric enhanced example examples exhibit feature filter fitting frayed frequency future hamburg help hitherto hypothesis in vivo incompatible indicated initial investigate investigated investigating investigation lesion lesions lier like limited local locally located magnitude malignancy malignant measured median medical middle opens operator overview parabola patients permeability peter phantom phys post potential properties reconstructed reconstruction reduce reduced regarded reliably restricted roughly scale science significantly specificity spin staging step structure studies subsequently subtraction suggested suspicious system systematic technical thank theory tissue tomography tool towards trans tries tumor tumors turbo upper volunteer white