Meeting Banner
Abstract #3318

Improved Detection of Subcortical Resting State Networks in Functional MRI Using Multi-Echo Simultaneous Multi-Slice Acquisition

Valur Olafsson1, Prantik Kundu2, Chi Wah Wong1, Jia Guo3, Peter A. Bandettini4, 5, Eric Wong1, Thomas Liu1

1Center for Functional MRI, UCSD, La Jolla, CA, United States; 2Section on Functional Imaging Methods, NIMH, Bethesda, MD, United States; 3Center for Functional MRI, University of California San Diego, La Jolla, CA, United States; 4Section on Functional Imaging Methods, National Institute of Mental Health, Bethesda, MD, United States; 5Functional MRI Facility, NIMH, Bethesda, MD, United States

Resting-state functional connectivity of human subcortical structures is of a particular interest due to its role in common cognitive functions. In this study we investigated the detection performance of subcortical resting-state functional connectivity networks, when using a multi-echo simultaneous multi-slice (MESMS) acquisition to increase the number of volumes collected per scan time, as compared to a multi-echo single slice acquisition. Our results showed that higher acquisition efficiency provided by MESMS provided an increase in the robust detection of subcortical networks.

Abstract PDF Presentation Video

Keywords

able acceleration accepted achieves acquisition anatomical archives artifact automatic automatically becomes bilateral blipped bold brain called channel characterizing coefficients coil collect collected collecting combined comparing component components computed concatenated confounds conjugate connectivity consistent correlated correlation coverage cross decomposed decreases deep described detection differentiate disease done echoes effectively either emerged episodic evaluated every excitation extract eyes facilitates facility fast fixation fold form function functional generated goodness gradient highest human identification importantly improve improved improvement increasing independent indicates investigated iterative listed longer manner maps matrix medical memory metric minutes networks neurology noise nova open optimally original particular performance peter physiological placed play posse potential previously prone pulse receive recent reconstruct reconstruction reduce reduces regularized removal representative resolution resting robust role roughness sacrifice sampling schemes section seed segmentation sense sets shortest simultaneous slice slices smith space spatial spatially structures subject subjects summarize system table temporal third trajectory typical verbal visible volume volumes ways whole