Meeting Banner
Abstract #3303

Functional Connectivity Alterations in Asymptomatic High School Football Players

Trey Shenk1, Kausar Abbas1, Evan Breedlove2, Victoria N. Poole3, 4, Katherine Breedlove5, Larry Leverenz5, Eric Nauman2, 4, Thomas Talavage1, 3, Meghan Robinson, 36

1Electrical Engineering, Purdue University, West Lafayette, IN, United States; 2Mechanical Engineering, Purdue University, West Lafayette, IN, United States; 3Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States; 4Basic Medical Sciences, Purdue University, West Lafayette, IN, United States; 5Health and Kinesiology, Purdue University, West Lafayette, IN, United States; 6Translational Research Center for TBI and Stress Disorders (TRACTS), VA Boston Healthcare System, Boston, MA, United States

We have explored resting state functional connectivity in asymptomatic high school American football players and a cohort of non-contact athletes peers. Seed-based default mode network (DMN) analysis reveals that while the total number of voxels included in the DMN did not change significantly with hits, the location of the DMN, as defined by number of voxels in MarsBaR regions, did. Independent component analysis (ICA) on all sessions was used to find stable networks. Pairwise correlations between networks were significantly different in players than controls in 8 of the 15 pairs, and further were correlated with hits in some cases.

Abstract PDF Presentation Video

Keywords

abnormal achieved aged alterations analyzed apart asymptomatic athlete athletes avoid basic biomedical blows brains characterizing clinically coefficient comparing component concussions connectivity considers consistent contact control controls correlated correlation correlations dashed default defined detectable diagnosed differ disorders electrical engineering examples exhibiting expected extent find fisher football functional head health healthy helmets help hits identified identify identifying impacts impairment included independent indicate indicating installed inter intra least leave library local location long male many measured mechanical medical melodic metric metrics mode network networks neural noting oxford pairs participated participation peers play players posterior presence press previous primary project rank receive received recruited regular repetitive response resting school schools sciences season seasons seed sessions significance significantly software spaced sport start stress subject subjects subnetworks system task telemetry term tracts trainers transform translational trauma trey types version visual weeks west worth