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Abstract #3230

Varying Frequencies of Flickering Checkerboard in Anisometropic Amblyopes: An fMRI Study

Reena Singh1, S. Senthil Kumaran2, Rohit Saxena1, Vimla Menon1, Pradeep Sharma1

1Dr.R.P. Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India; 2Department of NMR, All India Institute of Medical Sciences, New Delhi, Delhi, India

Visual acuity is decreased in one or both eyes in Amblyopia. We studied BOLD responses on visual stimulation using black and white checkerboard flickering at different frequencies (4, 8 and12 Hz) in unilateral Anisometropic Amblyopes and observed the maximum visual cortex BOLD activation observed at 8 Hz correlates.

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Keywords

abnormal activation activity acuity addition affected anatomical anterior ascribed axial binocular black blood body bold brain carried caused cerebellum cerebral channel checkerboard closed cluster clusters cognitive coil compatible contrast converted coordinates correlates cortex cues decrease decreased deprivation developed dimension dominant earlier estimation exhibited extra eyes fellow flickering flow frequencies frontal function goggles head immaturity inferior institute interaction journal lingual material matrix medical metabolism neurology nucleus occipital occurring ophthalmic orientation patients pattern planar post processing projected refers resolution responses scanner sciences sensitivity separately slice slices spatial stimulation stimulus striate studies suggestive superior table template temporal threshold unilateral varying vernier version viewing vision visual volumes wherein white whole