Meeting Banner
Abstract #3206

in-vivo High Resolution Diffusion Tensor Imaging of the Human Heart at 3T: Fat Suppression in the Presence of B0 Field Inhomogeneities

Jack Harmer1, Christian T. Stoeck2, Rachel W. Chan3, Nicolas Toussaint1, Constantin Von Deuster2, David Atkinson3, Sebastian Kozerke, 12

1Division of Imaging Sciences and Biomedical Engineering, Kings College London, London, United Kingdom; 2Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; 3Centre for Medical Imaging, University College London, London, United Kingdom

In recent work diffusion acquisition schemes that employ stimulated echoes (STE) have been used to allow diffusion tensor imaging of the beating heart. Higher order localized image based shimming can partially compensate for the increased field inhomogeneity at high field strength but, at the same time, compromises the effectiveness of fat saturation techniques such as SPIR across the entire field-of-view. We present a dual navigated STE sequence with Slice Selective Gradient Reversal (SSGR) applied to the second and third RF pulses in order to suppress the fat signal in in-vivo data of the human heart at 3T.

Keywords

acquisition acquisitions address advanced allow allows applied assessed away background bandwidth beam best biomedical bulk cardiac carried carrying channel circumferentially coded coil college combination compensate compromises create cycle decoding described deviations diaphragm diffusion division dual duration echoes effectiveness efficiency enabled encoding engineering entire example failed field fractional gate gating gradient gradients harmer heart helps highly human improve improving in vivo inherently inhomogeneities inhomogeneity institute intensity jack kingdom kings limitation lobes localized maps medical middle minutes module motion moving muscle navigated navigation navigator organs oriented outside park part partial partially parts pencil permitting placed ploying position post previous principal problems proved pulse pulses readout receive recent reconstruction reducing related remain repeat required resolution respectively respiratory restricting reversal robust saturation scanning schemes sciences selective sense sensitive severely shim shimming shims shot simplified slice steam stimulated strengths studies successful supported suppression susceptibility system tended tensor tensors thereby third triggered ventricle ventricles version volume volunteers whilst windows