Iris Asllani1,
Shazia Dharssi1, Marykay Pavol1, Ronald L. Lazar1,
Randolph S. Marshall1
1Columbia
University, New York, NY, United States
There is converging evidence that cerebral hemodynamic failure affects cognitive function in carotid artery disease, but inconsistent methods of measuring both the behavioral and the hemodynamic state have hindered this line of inquiry from influencing clinical management. Here, we present preliminary data from patients with 100% carotid stenosis on whom we measured hemodynamic parameters such as baseline and activation CBF as well as arterial transit times (ATT) using PCASL fMRI.