A New Method for Quantifying Chemical Exchange Rates from CEST MRI Using the Solutions to the Time-Dependent Bloch Equations with and Without Spin Locking

Keywords

account accuracy achieve added adopted agents almost although analogy applied approaches assume assumed available axis back bias bulk characteristics chemical circles clearly closed component computation computed conditions considerably consisting contrast contrasts corresponds degree denote denotes dependent diagram dimensional duration easily effective either engineering equation equations equilibrium error estimating estimation evaluate example examples exchange exchangeable expand exponential extended fast field flipped frequencies frequency functions furthermore hand holds illustrates illustrative increasing indicating investigate investigating irradiation japan known lease locked locking longitudinal magnetization magnetizations materials matrices matrix mechanism medical model models modifying necessary noise nonlinear noted novel numerical nutation offset often open operation optimal ordinary physics plots pool pools preferable probe propose proposed protons pulse quantifying quantitatively recently reduced reliable represent respect respectively rotation saturation simple simulations slightly smaller solute solution solutions solver solving spin spins sqrt square squares statistical studies suggest superscripts taking thermal tissue transfer transverse treated true type useful visualized water