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Abstract #2526

Amide Proton Transfer (APT) Imaging for Grading of Glioma

Ge Zhang1, Xianlong Wang1, Shilong Lu1, Jinyuan Zhou2, Zhibo Wen1

1Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China; 2Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States

We explored the imaging features of different grades of glioma using Amide Proton Transfer MR Imaging at 3 Tesla. Results showed that the average APT signal intensities of the viable tumor cores were significantly higher than those of peritumoral edema or normal-appearing white matter in both low-grade and high-grade glioma. The average APT signal intensities of the viable tumor cores were significantly higher than in low-grade glioma. APT imaging provides additional diagnostic information to characterize different grade of glioma.

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Keywords

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