Meeting Banner
Abstract #2522

Optimal Partial Fourier Reconstructions in Electron Paramagnetic Resonance Imaging

Alan B. McMillan1, Hyungseok Jang1, Sankaran Subramanian2, Murali C. Krishna2

1Radiology, University of Wisconsin, Madison, WI, United States; 2Radiation Biology Branch, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, MD, United States

Electron paramagnetic resonance imaging (EPRI) employed using single-point (SP) imaging techniques offers the capability to dynamically image in vivo tumor oxygenation. While highly specific, current capabilities for high spatial resolution dynamic imaging are limited. Recently, we have investigated partial k-space acceleration techniques for SP-EPRI. In this work, we show that the SP-EPRI imaging technique is highly suited to PF techniques due to its tractable phase characteristics, and that performance of each method is dependent upon image matrix size.

Keywords

acceleration achieved acquisition acquisitions benefit better biology branch cancer capabilities capability cells characteristics combination combined comparable conjugate corrected correction delay density dependent determine dynamic dynamically electron elliptical employed encoded encoding error evaluated evaluation even exhibit expected extend femoral fields findings full fully generated good gradient health highly identical identify implanted improve in vivo includes inherently institutes investigated just known larger limited little magnitude matrix middle modality mouse muscle national offers operating optimal original overall oxygenation paramagnetic partial performance phantom poorly press quality quantitative radiation radiology recently reconstructed reconstruction reconstructions reduced reduces remaining resolution resolutions respective resultant sampled sampling schemes smaller space spatial spectrometer strategies strategy suited symmetry temporal tractable tumor upon versus zero