Meeting Banner
Abstract #2436

MR Elastography Using Switching-Gradient-Induced Vibration of the Patient Table - Assessment of Reproducibility -

Mikio Suga1, 2, Takayuki Obata2, Hajime Ikeda1, Atsuhisa Koyama1, Tetsuya Wakayama3, Riwa Kishimoto2

1Graduate School of Engineering, Chiba University, Chiba, Japan; 2National Institute of Radiological Sciences, Chiba, Japan; 3GE Healthcare Japan, Hino, Tokyo, Japan

Magnetic resonance elastography (MRE) is a noninvasive technique for measuring tissue viscoelasticity. Switching-gradient(s)-induced vibration (SGIV) can be used as a mechanical driving mechanism for MRE. The advantage of this approach is that it can be easily adapted for clinical application, but the reproducibility of measurements has not been confirmed. To evaluate reproducibility of MRE scanning with SGIV (MREwSGIV), this study compared shear wave amplitudes in gel phantoms of different weight and measured the viscoelasticity of the human brain at specific mechanical resonance frequencies twice. The results suggest that MREwSGIV enables reproducible measurements of brain elasticity.

Abstract PDF

Keywords

accurate acquisition adapted advantage amplitude amplitudes anal application applied array assessment axis body brain channel clinical coil conditions confirmed cycles cylindrical decreased decreases direct driving duration easily eight elasticity enables engineering evaluate female field frequency gradient gradually graduate harmonics head healthy homogeneous human identical in vivo independent induced institute interval inversion japan known loss maps materials matrix measured measuring mechanical mechanism middle moduli modulus motion national noninvasive offsets patient peaks phantom phantoms placed probably protocol pulse radiological reason repeated repetition reproducibility reproducible respectively scanning school science sciences selected sensitizing separated shear simulate simulating slice slices spacing spin statistical storage successfully suggest switching table tank tissue twice vibration view viscoelasticity viscosity water wave waves weighed years