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Abstract #2242

EEG Correlates of Time-Varying BOLD Functional Connectivity

Catie Chang1, Zhongming Liu2, Michael C. Chen3, Xiao Liu2, Jeff H. Duyn1

1Advanced MRI Section, LFMI, NINDS, National Institutes of Health, Bethesda, MD, United States; 2Advanced MRI Section, LFMI, NINDS, NIH, Bethesda, MD, United States; 3Dept. of Psychology, Stanford University, Stanford, CA, United States

While resting-state functional connectivity (FC) has been observed to vary substantially over time-scales of seconds to minutes, the origins and relevance of these dynamics are not well understood. Here, we use simultaneous EEG-fMRI and a sliding-window analysis to investigate the electrophysiological correlates of within-scan fluctuations in FC between default-mode (DMN) and dorsal attention (DAN) networks. Fluctuations in alpha power were significantly correlated with fluctuations in DMN-DAN connectivity as well as in the degree of DMN-DAN anti-correlation. These results suggest an electrical signature of non-stationary DAN-DMN FC, potentially reflecting variations in vigilance or attentional states.

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Keywords

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