Meeting Banner
Abstract #2240

Stability of Resting-State Brain Activity Fluctuations Across Time: Evidence from fMRI and MEG

Om Bhatt1, Jed Meltzer1, Bernhard Ross1, J. Jean Chen1

1Rotman Research Institute, Baycrest, University of Toronto, Toronto, ON, Canada

Magnetoencephalography (MEG) is potentially valuable in clarifying the physiological mechanisms of resting-state fMRI-based functional connectivity. However, MEG and fMRI experiments cannot be performed simultaneously on the same subject. In this work, we present evidence for a stability of intrinsic brain activity across time. This stability is higher in certain brain regions, and higher during eyes-open than in eyes-closed resting state. These findings will enhance our ability to capitalize on the spatially resolved neuro-electric information from MEG to inform resting-state fMRI interpretations of brain activity. Future work will address the link between these spectral features and connectivity.

Keywords

acquisition activity adaptive address alpha among apart applications applied assess audience autism bands beta bold brain calculating capitalize capsules certain characterizations characterize class clinical closed collected complemented complements computed conducted conn connectivity consistent correlation correlations course cross days default dementia densities derive derived detailed disorders distinguishing distribution duration elusive established evidence examined eyes facilitated features filter finally findings fixate fluctuations fluid fractional frequency front function functional fusion future global gradient head healthy hours increasing independent inform inter interpretations intra linear link masks matrix measure measures mechanisms medial median minutes modal modalities mode model network networks neurological neurophysiology noise novel nuisance open particularly pass physiological placed power powers preprocessed press previously prominent reason record recorded regressors regularization remove reproducibility required requires researchers resolve resolved resting sclerosis sensor series session sessions simultaneously slice source spatial spatially spectral stability studied subject subsequently suggesting system target theta third toolbox valuable variable variance variate white years