Stephen Jones1,
Erik B. Beall2, Jorge A. Gonzalez-Martinez1, Blessy
Mathew1, Dileep Nair1, Imad Najm1, Michael
Phillips1, Ken E. Sakaie1, Myron Zhang1
1Cleveland
Clinic Foundation, Cleveland, OH, United States; 2Cleveland
Clinic, Cleveland, OH, United States
We study the correlation between diffusion weighted imaging (DWI) measures of structural brain connectivity and electrophysiological connectivity obtained from intracranial electrodes in epilepsy patients. We have collected data from four patients, each with around 150 electrode contacts implanted, and our analysis suggests that the correlation between DWI-based connectivity and electrophysiological connectivity is only modest and still uncertain, which may shape how we interpret DWI data and results.