Meeting Banner
Abstract #2138

A Diffusion MRI Resource of 80 Age-Varied Subjects with Neuropsychological and Demographic Measures

Ryan P. Cabeen1, Ksenia Andreyeva2, Mark E. Bastin2, David H. Laidlaw1

1Brown University, Providence, RI, United States; 2University of Edinburgh, Edinburgh, United Kingdom

The primary purpose of this work is to provide a resource of high angular resolution diffusion MRI datasets of 80 normal volunteers aged 25-64 together with neuropsychological testing data spanning general cognitive ability, memory, and information processing speed. To support the value of these data, we demonstrate statistical correlations between age and tract-based metrics calculated automatically from the data. The metrics are a function of fiber count, length, diffusion rate, and diffusion anisotropy; the statistical relationship to age was modeled with linear regression.

Abstract PDF

Keywords

aged aging alignment analyses anisotropy approved atlas audience automatically beta blue brain brown bundle bundles chord coefficient cognition colors computational computed connections connectivity control corrected correction correlation cortical count covariate created culled curve custom dale dataset datasets decreases decreasing demographic develop developing diffusion diffusivity discovery downloads equal example existing exploratory extraction fiber fibers finally flirt forceps fractional frontal function general graph gray healthy human hypothesis included incorporated increasing indicate indicated induced inferior integration integrity intended length linear linearly lobe lobular longitudinal male mapped mark memory metrics minor modeled motion mutual negative neurobiology numerical numerous occipital opportunity pair parietal part population positive potential previous primary principal project protocol random registration registrations regression relationship removing reported request resolution resource respectively rigid roughly scanner segmentation sign software space spanning speed statistical structures studies subject subjects summed support table tables temporal tensor threshold together tract trends type types vectors volume volunteers website white years zero