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Abstract #2119

Test-Retest Reliability in Fibre Orientation Distribution (FOD) Measurements in HARDI Data

Kai-kai Shen1, Stephen Rose1, Jurgen Fripp1, Katie McMachon2, Greig de Zubicaray3, Nicholas Martin4, Paul Thompson5, Margret Wright4, Olivier Salvado1

1Australian eHealth Research Centre, CSIRO, Herston, Queensland, Australia; 2Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia; 3School of Psychology, University of Queensland, Brisbane, Queensland, Australia; 4Queensland Institute of Medical Research, Brisbane, Queensland, Australia; 5Imaging Genetics Center, Laboratory of Neuro Imaging, UCLA, Los Angeles, CA, United States

We evaluated the test-retest reliability for measures based on the fibre orientation distribution (FOD) using constrained spherical deconvolution (CSD). We derived measurements in the peak direction identified from the FOD, and evaluated the test-retest reliability for these FOD peak amplitudes using the intra-class correlation (ICC) coefficient. We visualized the ICC coefficients on the FOD orientation plot. We compared the reliability of measuring the FOD peak amplitudes and the fractional anisotropy (FA) derived from the diffusion tensor imaging (DTI) model.

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Keywords

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