Meeting Banner
Abstract #2098

Potential of Diffusion Tensor Imaging as a Virtual Dissection Tool for Cardiac Muscle Bundles: A Pilot Study

Seongjin Choi1, Ria Mazumder2, Petra Schmalbrock1, Michael V. Knopp1, Richard D. White1, 3, Arunark Kolipaka1, 3

1Radiology, The Ohio State University, Columbus, OH, United States; 2Electrical and Computer Engineering, The Ohio State University, Columbus, OH, United States; 3Internal Medicine, The Ohio State University, Columbus, OH, United States

Diffusion-based tractography has the potential to delineate complex cardiac muscle fiber architecture. We explored fractional anisotropy distribution, angle and length threshold dependency of tractography in a fixed heart specimen. Tracking method used in the brain research was applied straightforwardly. Among three tracking constraints, seeding FA value and minimum fiber length threshold noticeably affected the tractography results. z-component of principal eigenvectors was useful index for subepi/subendocardium segmentation. Three long fiber bundles of interest and subepi/subendocardium were segmented as a demonstration of this approach.

Abstract PDF Poster PDF

Keywords

achieve actual affect affected although among anatomy anisotropy applied applying architecture buffered bundle bundles cardiac carried circulation complex component computer conducted constant constraints correction degrees delineate demonstration dependency depending derivatives details determine deterministic diffusion dissection distance distortions distribution drastic easily eddy editor eigenvalues eigenvectors electrical engineering evaluated examples explored extended extraction facilitate feasibility fiber fibers fixation fixed formalin fractional frequently fresh generate goal heart hence in vivo included influence initial inner internal interval investigate isotropic kept layers length library long make many masked materials matrix medicine might minimally months muscle muscles neutral next noticeably observe organization orientation outer oxford pilot planar porcine postmortem potential principal process radiology rarely related remove repeated reported reveal room seeding segment segmentation segmented segmenting selected shorter shot significantly simple slices software specimen spin step steps stored studied studies subtle temperature tensor threshold tool tracked tracking tract turned turning ultimate underperformed underwent unfilled untracked useful varying ventricle virtual white