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Abstract #2018

2D-GRAPPA Accelerated FID Based MRSI of the Brain at 7T

Bernhard Strasser1, Gilbert Hangel1, Stephan Gruber1, Siegfried Trattnig1, Wolfgang Bogner1, 2

1Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, United States

In this work the excess signal-to-noise ratio per unit time that was provided by the use of measuring with an FID based sequence at 7T, and performing an optimized coil combination was traded for a substantial reduction in scan time, thus, enabling high resolution MRSI measurements in clinical relevant times. This trade-off was achieved by using optimized 2D-GRAPPA acceleration. The acquisition times were reduced to below four minutes with a spectral quality that is comparable to that of a more than eight times longer measurement with a volume coil. Five volunteers were measured to prove the feasibility of the method.

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Keywords

accelerated acceleration acceptable acquisition acquisitions addition additional aliasing applications array artifact artifacts artificial audience auto available best better biomedical bonds brain brains calibration causes channel chosen clinical clinically coil coils combination comparable comparing computed computing correct decrease delay delays density disease diseases durations efficiently eliminate elliptical enhancement equal evaluation feasible field filtered fitted five fixed full fully gain generalized gilbert gradient gradients hamming henning highest important improve investigating lead long longer maps matrix measure medical metabolic metabolites middle minutes much neurological noise offers omitting operator operators optimize optimized outer overall parallel partially parts pattern patterns post power powers proceedings processing proton providing pseudo quality radiology radius reconstructed reconstructions reduced reduction remaining required resolution respectively reversed sampled sampling scientists sclerosis script serve sets several short significantly simulated slow smaller space spectra spectral spectroscopic spectrum speed spiral spots still strength target tool traded tumors ultra unequal uniform unit variable volume volunteers