Meeting Banner
Abstract #1984

A Measurement Setup for Combined Chlorine (35Cl) and Sodium (23Na) MRI of the Human Brain

Armin M. Nagel1, Titus Lanz2, Dominik Berthel2, Frank Resmer2, Wolfhard Semmler1, Reiner Umathum1

1Dpt. of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; 2Rapid Biomedical, Rimpar, Germany

A dual tuned head coil for combined 35Cl/ 23Na imaging is presented. For evaluating sensitivity optimization, two versions were built: one with a 23Na trap in the 35Cl resonator, one without. By including 23Na traps into the 35Cl resonator, the B1 efficiency of 35Cl versus 23Na can be controlled. The version with 23Na traps was evaluated in phantom and in vivo imaging. Both channels show good B1 efficiency and SNR performance. The presented setup allows for combined 23Na/ 35Cl MRI without repositioning of the patient.

Keywords

abundant according acquisition adapted addition additional allows anion assist association assumed audience better biomedical birdcage blocked body brain built cancer cell cellular channel channels chlorine chosen clinical coil coils combined comparable contains controlled correction definition density dependence desirable determined double drop dual duration efficiency electrical electronic evaluate examinations excitability expected field filtering fold frank frequencies frequency fulfill furthermore good hamming head healthy highly homogeneity human hypothesizing in vivo intermediate involved kirsch larger length lies long loss losses made magnitude manufacturers many maps matched measured morphological national neglected nicely noise nominal normally optimization patient performance phantom physicians physics physiological power predicted projection projections proton pulse quadrature quality radial rapid reconstruction regulation repositioning required resolution resonant resonator resonators restrictions sector sensitivity sets setup setups simple since slices smaller sodium solution spherical sqrt steps studies sufficient system table target theoretically transmit transport transversal traps tuned unfeasible version versions viability voltages white whole workbench years yield yielded