Accumulation of Micron Sized Iron Oxide Particles (MPIOs) in Endothelin-1 Induced Focal Cortical Ischemia in Rats Is Independent of Cell Migration

Keywords

abolish accumulate accumulation aimed animals anti appropriate arrows association attempt become biological blue brain brains briefly carefully carried cell cells circles clear complicates confirmed confirming confound confounded contrast control coordinates coordination cortex cortical course dark days death delivery dependent derived describe detected detection diluted disease early endogenous enhanced event expected extent fault fluorescence fluorescent focal foot frozen fully gradient green hemisphere hours identify immediate immediately impaired indeed independent induced induction infused infusion infusions initial injected injection injections injured injury insult integrity intensity interpretation involves iron labeled labeling lateral leakage localized magnetite mapping maps mechanism methodological micron microscopy migration migratory model neurology niche notably onset oxide particles patterns population positive post prevented previously prior processed rabbit radiology rapid rather rats reduced reduction regulation revealed rodent saline scale scanned sections separated seven site sites staining stem stroke structure successful suggest suggested syringe third track treated usage variations ventral ventricle verified week yellow zone