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Abstract #1810

MR-Guided Thermotherapy of Abdominal Organs Using a Robust PCA-Based Motion Descriptor

Baudouin Denis de Senneville1, 2, Mario Ries2, Chrit T.W. Moonen2

1IMB, UMR 5251 CNRS/University Bordeaux 1/INRIA, Talence, Gironde, France; 2Imaging Division, UMC Utrecht, Utrecht, Netherlands

Thermotherapies can now be guided in real-time using magnetic resonance imaging. This technique is gaining importance in interventional therapies for abdominal organs. An accurate on-line estimation and characterization of organ displacement is mandatory to prevent misregistration and correct for motion related thermometry artifacts. Here we describe the use of a Principal Component Analysis to detect spatio-temporal coherences in the physiological organ motion and to characterize in real-time the complex organ deformation. During hyperthermia, incoherent motion patterns could be discarded, which enabled improvements in the compensation of motion related errors in thermal maps, as well as in the motion estimation robustness.

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Keywords

abdominal acquisition activities addition address addresses affine allowed amplitude assist assumption background basis bipolar breathing cardiac characterization characterize clinical coding coherences compatible compensated compensation complex component computed conditions contributions correct correction coupled dash deformation descriptor descriptors designed detect dimensional discard discarded displacement domain dynamic eigenvectors employed enabled errors estimation evaluated evolution experiment expressed field fields flow frame free general generated gives global gradient guided healthy heated heating histogram importance improved improvements in vivo incoherent instant intensity intervention kidney learned learning linear liver local location mandatory maps matrix medicine minutes model motion motorized navigator noise object optical organ organs parameterized patterns periodic periods physiological pixel planar porcine positioned precision preparative principal prior properties proposed radionics rapid real recalled reduced registered related relevant renders representation resolution respectively respiratory robust separate several shot since solver spatial step suitable susceptibility sustained target temperature temporal therapies thermometry threshold tissue trajectory transformation translational twelve variation variations vector violated volunteers