Eleftheria Panagiotaki1,
Daniel C. Alexander2, Roger Bourne3
1Centre
for Medical Image Computing, University College London, London, United
Kingdom; 2Centre for Medical Image Computing, Dept Computer
Science, University College London, London, United Kingdom; 3
Discipline of Medical Radiation Sciences, Faculty of Health Sciences,
University of Sydney, Sydney, Australia
This study used high-field high-gradient diffusion-weighted (DW) MRI of fixed prostate tissue to explore the key components of an accurate biophysical model for obtaining future biomarkers of cancer and other pathology. We acquired DW-MRI with a rich imaging protocol and selected for modelling two tissue types (from the central and peripheral zone ) to compare four diffusion models.