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Abstract #1678

Feasibility of 3Tesla MR-Guided Biopsy of Soft Tissue Tumors: Site Selection by the Use of Dynamic Contrast Enhanced (DCE) MR, Diffusion Weighted Imaging (DWI), and Multivoxel 1H-MR Spectroscopy (1H-MRS)

Iris-Melanie Noebauer-Huhmann1, Gabriele Amann2, Martin Krssk3, Pavol Szomolanyi4, Joannis Panotopoulos5, Michael Weber1, Philipp Funovics5, Martin Dominkus5, Christian Czerny1, Reinhard Windhager5, Siegfried Trattnig4

1Department of Radiology, Medical University of Vienna/Vienna General Hospital, Vienna, Austria; 2Department of Pathology, Medical University of Vienna/Vienna General Hospital, Vienna, Austria; 3Department of Internal Medicine III, Medical University of Vienna/Vienna General Hospital, Vienna, Austria; 4High field MR Center of Excellence, Department of Radiology, Medical University of Vienna/Vienna General Hospital, Vienna, Austria; 5Department of Orthopaedic Surgery, Medical University of Vienna/Vienna General Hospital, Vienna, Austria

Accurate diagnosis of soft tissue tumors requires an optimized biopsy technique for preoperative histology. We performed staging 3T-MR of soft tissue tumors with MR-guided biopsy in 52 patients.In 49/52 patients with final surgical histology, the diagnostic yield was 97.8% (48/49). The accuracy in predicting the dignity was 100% (48/48), the accuracy in providing a definitive tissue diagnosis was 89.3%, and the accuracy in predicting the grade of the tumor was 93.6%. Our preliminary study indicates that biopsy can be performed accurately and safely by DCE-targeted MR guidance at 3T, using the DCE staging sequence in a combined staging/biopsy MRI.

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Keywords

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