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Abstract #1644

Repeatability of Diffusion Tensor Imaging and Water-Fat MRI in Lower Extremity Muscles in Children

Skorn Ponrartana1, Houchun Harry Hu1, Kristine E. Andrade1, Jonathan M. Chia2, Thomas G. Perkins2, Tishya A. L. Wren3, Vicente Gilsanz1

1Radiology, Children's Hospital Los Angeles, Los Angeles, CA, United States; 2Philips Healthcare, Cleveland, OH, United States; 3Orthopaedic Surgery, Children's Hospital Los Angeles, Los Angeles, CA, United States

This work evaluates the repeatability of chemical-shift water-fat MRI and diffusion tensor imaging measures of muscle in a wide age range of healthy children. Mean difference between measures, intra-rater agreement, and inter-rater agreement were calculated. Both water-fat MRI and diffusion tensor imaging demonstrate minimal mean difference with excellent agreement. Of these techniques, water-fat MRI had the higher level of agreement. Additionally observed was a statistically significant association of muscle fat percentage with age. Water-fat MRI and diffusion tensor imaging can be performed in a clinical setting across a broad age group with good repeatability.

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