Meeting Banner
Abstract #1508

Quantitative Liver MRI Combining Phase Contrast Imaging, Elastography, and DWI: Assessment of Test-Retest and Post-Prandial Effect. Prospective Study at 3T.

Guido H. Jajamovich1, Hadrien A. Dyvorne1, Ersin Bayram2, Claudia Donnerhack1, Richard L. Ehman3, Bachir Taouli1

1Mount Sinai School of Medicine, New York, NY, United States; 2GE Healthcare, Waukesha, WI, United States; 3Mayo Clinic, Rochester, MN, United States

Liver blood flow and metabolism can be altered in postprandial state, which may induce changes in quantitative MRI techniques such as phase contrast (PC), MR elastography (MRE) and DWI. In this study, we assess reproducibility in fasting conditions and the post-prandial effect on the following metrics: portal venous blood flow/velocity, liver stiffness measured with MRE and liver ADC measured with DWI in 11 subjects. Portal venous flow/velocity and liver stiffness increased significantly after caloric intake, whereas ADC did not show significant changes.

Abstract PDF Poster PDF

Keywords

able affected altered approved assess assessment axial breathing caloric chronic cirrhosis cirrhotic clinic clinical coefficients combining compute computed conditions consider contrast cutoff dashed decreased detect detection diagnostic differentiate diffusion disease drawn elevated enrolled ensure excellent expected exponential fasting fibrosis fitting flow food free fully good grant healthy hepatic hours hypertension indicate initially intake interpreting invasive kcal larger lead liquid liver lobe maps mayo meal medicine metrics might mono mount needed needs observation optimal paired patient patients perpendicular placing plus portal post postprandial potential previously prospective pulse quantifies quantify quantitative ranging recently removed reproducibility respectively retest scanned scanner school significance significantly since slice slices stiffness subjects supported table triggered twice underwent variation vein velocity verified volunteers