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Abstract #1500

Detection of Pulmonary Proton Density at 6.5mT

Samuel Patz1, 2, Mikayel Dabaghyan, 13, Matthew Rosen4, 5, Mirko I. Hrovat3

1Radiology, Brigham & Women's Hospital, Boston, MA, United States; 2Harvard Medical School, Boston, MA, United States; 3Mirtech, Inc., Brockton, MA, United States; 4Martinos/MGH Biomedical Imaging Center, Charlestown, MA, United States; 5Physics, Harvard University, Cambridge, MA, United States

The purpose of this work was to demonstrate the feasibility of detecting changes in pulmonary proton density at very low field strength (6.5mT). A 4-inch diameter RF surface coil was applied to the chest and FIDs detected at different lung volumes. Differences in the acquired spectra easily demonstrated changes in lung density. Eventual application to a portable, ICU compatible planar magnet is envisioned in order to detect changes in lung patency in subjects with acute lung injury.

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Keywords

actual acute adjust application approximately asked bandage bedside biomedical body breath breathing build building butler capacity care chest claim coil conclude constructed defined density detect detected detection diameter distinct effectively establish exhalation expected expiration feasibility feedback field frequency full function functional goal gradients hold hospital important improve inch included indicate injury inside inspiration integrated integration intensive known localization located long lung made magnet majority manner mechanical medical much near noise note operating optimally part particular patent patients peak physics portable posterior profile properties proton pulmonary quantitative radiology regional relaxed residual resolution room sampled scanner school scientists secured settings shielded spatial spectra spectral spectrum step strength subject subtracted supported surface systems term tissue traditional traditionally transported unit vast ventilation visually volume volumes whole women