Meeting Banner
Abstract #1411

Three Dimensional Myocardial T1 Mapping During Free-Breathing

Sebastian Weingrtner1, 2, Mehmet Akakaya1, Warren J. Manning1, Reza Nezafat1

1Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States; 2Computer Assisted Clinical Medicine, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany

Myocardial T1 mapping is an emerging technique for improved evaluation of scar and fibrosis in the myocardium. Commonly 2D T1 mapping is performed with one breath hold per slice. We propose a novel free-breathing 3D T1 mapping sequence to benefit from the improved SNR and enable better spatial coverage and spatial resolution. The proposed scheme consists of multiple, interleaved inversion-recovery images. A joint prospective and retrospective navigator gating scheme is applied to compensate for respiratory motion. The acquired T1 maps were of improved homogeneity compared to MOLLI and free of motion artifacts induced by improper breath holds.

Abstract PDF

Keywords

acceptance accepted achieved acquisition acquisitions address allow already among arrow artifact artifacts assisted bars beginning beth blood breath breathing central clinical comparing compartment compartments compensation consists contrasts conventionally coverage create creates curve cycle deaconess defined depicted detection develop diagnostic diffuse dimensional discarded dummy effective efficiency emerging enables ensure error estimation evaluated feasibility fibrosis fitting fold free fully gated gating healthy heart hold holding holds homogeneity improper improved in vivo indicates individual induced inherently injection intensities interleaved interleaves inversion joint limit limitations locker longitudinal look magnetization manning mapping maps medical medicine minutes model motion moves myocardial myocardium navigating navigator novel numerous onto outer outside periods phantom proposed prospective quantitatively recovery reduction remains repeated represent representative require resolution respiratory rest retrospective retrospectively scheme school segment segmented sense sensing shot slice sought space spatial statistical subjects subsequently suffers sufficient system terms throughout tool trend triggering underestimating utilizing variation varied various ventricles volumetric volunteer warren window wise