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Abstract #1399

Assessment of Myocardial Reperfusion Injury with Magnetic Resonance Imaging: Segmental Susceptibility-Weighted Phase, Late Gadolinium Enhancement and Rest Perfusion Imaging

James William Goldfarb1, 2, Usama Hasan1, Wenguo Zhao1, Jing Han1

1Department of Research and Education, Saint Francis Hospital, Roslyn, NY, United States; 2Program in Biomedical Engineering, SUNY Stony Brook, Stony Brook, NY, United States

In patients with myocardial infarction, high-pass filtered (HPF) phase imaging was compared with quantitative resting myocardial perfusion and late gadolinium-enhanced (LGE) infarct imaging. Infarct to remote segmental upslope percent showed a similar reduction in resting perfusion with the presence of microvascular obstruction (MVO) and myocardial hemorrhage at all stages of myocardial infarction. Reduced segmental resting perfusion was a sensitive, but not specific indicator of MVO and intramyocardial hemorrhage. Susceptibly-weighted HPF-phase imaging represents a new quantitative, high quality method for the detection of myocardial hemorrhage and is associated with reduced resting perfusion and MVO.

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Keywords

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