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Abstract #1375

Contrast-Enhanced Look-Locker and Delayed-Enhancement MRI in Patients with Apical Hypertrophic Cardiomyopathy: Distribution of Myocardial Damages and Its Association with Risk Factors and Cardiac Function

Yasuo Amano1, Masaki Tachi1, Hitomi Tani1, Shinichiro Kumita1, Makoto Obara2

1Nippon Medical School, Tokyo, Japan; 2Philips Healthcare Asia Pacific, Tokyo, Japan

Apical hypertrophic cardiomyopathy (APH) showed myocardial hypertrophy and scarring dominantly in the left ventricular apex. The mass percentage of myocardial scarring is associated with the decrease in the LV ejection fraction and traditional risk factors plus family history of hypertrophic cardiomyopathy in APH. Conversely, we do not have to quantify myocardial T1 value for the risk stratification of APH, because the T1 value did not differ between the apex and other non-hypertrophied myocardium and had no association with the risk factors.

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Keywords

apex apical assessed association audience basal cardiac cardiologists cavity characterized cine clinical combination complications configuration contrast correlated damages death decrease delayed detected determine differ differed diffuse distributed distribution dominantly dysfunction either ejection enhanced enhancement evaluated even examined family fibrosis fraction function greater heart history hypertrophied hypertrophy identified indicates inversely japan lead like localized locker look mass measured medical modest moon myocardial myocardium occur pacific particularly patients percentage phenotype physicists plus pressure quantified quantify radiologists reduction reflect related risk scar scarred scarring school segments serious significantly sought spade stratification sudden table tachycardia target third traditional twenty unique ventricular wall whether