Meeting Banner
Abstract #1367

Black-Blood Preparation Vs. Bright-Blood for Myocardial T2p-SSFP Based T2 Quantification

Ina Vernikouskaya1, 2, Peter Bernhardt1, Wolfgang Rottbauer1, Volker Rasche1, 2

1Internal Medicine II, University Hospital of Ulm, Ulm, Baden-Wuerttemberg, Germany; 2Small Animal MRI, University of Ulm, Ulm, Baden-Wuerttemberg, Germany

Quantitative T2 mapping is required for the characterization of myocardial tissue. The superior performance of the black-blood preparation compared to the bright-blood data for myocardial T2* measurements in iron-overloaded thalassemia has been reported. Therefore the aim of this work was to compare the performance of the monoexponential and offset mapping algorithms for T2 quantification based on T2-prepared steady-state free precession imaging technique with and without black-blood preparation. The preliminary results obtained from 5 subjects showed that the offset model provide a more robust T2 decay curve fitting for myocardial T2 mapping compared to the simple monoexponential model in both bright- and black-blood data.

Keywords

able accuracy accurate acquisition address adopted although animal appears applied appreciated approaches appropriate array artifacts audience axis baden best bias black blood body borders bright capture cardiac carried causes characterization clearly clinical coil complicate consecutively consequently contrast correspondent correspondingly crucial curve curves cycle datasets decay decided defined derived detection diastole direct duration edema element evaluation every example exemplary experiment fits fitted fitting free generally generates gives good gradient hospital important improved in vivo included internal intervals investigate iron leading like loss mapping maps medicine minimized model modeled models motion motions myocardial neither noise offset often optimal overall overestimates overloaded particular patient patients performance peter phantom precession preliminary preparation prepared previous previously problem produces pulses pure quantification reduces refocusing reported representative reproducibility reproducible researchers respectively respiratory rise robust scanner short shorter simple simultaneously situation spin steady student studies suffer superior suppl suppression target tissue truncation typical underestimate validity whereas whether whole