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Abstract #1350

Association of Arterial Compliance Between Carotid Artery and Abdominal Aorta and Its Role in Assessment of Carotid Atherosclerotic Disease: A 3.0T MR Imaging Study

Li Jiang1, Huijun Chen1, Xu Han2, Zhensen Chen1, Rui Li1, Le He1, Chun Yuan1, 3, Xihai Zhao1

1Center for Biomedical Imaging Research & Department of Biomedical Engineering, Tsinghua University, Beijing, China; 2Department of Radiology, PLA General Hospital, Beijing, China; 3Department of Radiology, University of Washington, Seattle, WA, United States

Wall compliance, as a systemic biomechanical characteristic of degeneration of vessel wall, has been demonstrated to be associated with atherosclerosis disease risk. In this study, we investigated the correlation of wall compliance between carotid artery and abdominal aorta and its role in assessment of severity of carotid atherosclerosis. We found that compliance of carotid artery differed from abdominal aorta and was associated with abdominal aorta compliance as well as carotid atherosclerotic plaque burden. Our findings indicate that arterial compliance in one vascular bed might be an indicator for other vascular biomechanical characteristics and severity of atherosclerotic disease.

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Keywords

abdominal acquisition addition aging among analyzed aorta aortic arterial arteries artery assessment association asymmetric atherosclerosis axial beds best bifurcation bilateral biomedical black blinded blood body boundaries boundary burden calculations cardiac cardiovascular carotid cascade channel characteristic characteristics china cine coefficient coil common community compliance consensus coronary correlated correlation correlations crop cross custom debate defined degeneration delineation designed determine determined diastolic disease engineering evaluated example experienced field findings future general hypertension imported index indicating indicator investigated investigators local lumen male manual matrix maximal measure measured medical merge might minimize named normalized outlining participants plaque population pressure pressures previous property pulse radiology recruited reflects related renal resolution respectively reviewers risk role scanner sectional sectionally severity side sides significantly slice slices smaller software spatial status still stored strong strongly structure studies subjects suggest suggesting summarized summary system systemic systolic table traced turbo twenty underwent unit vary vascular vessel view visit wall whole workstation years yuan