Meeting Banner
Abstract #1337

Aortic Coarctation Alters Thoracic Aortic Hemodynamics Across a Large Age Range

Bradley D. Allen1, Alex J. Barker1, Julio Garcia1, Maya Gabbour2, Miachael Markl1, 3, Cynthia K. Rigsby, 12, Joshua D. Robinson4, 5

1Department of Radiology, Northwestern University, Chicago, IL, United States; 2Department of Medical Imaging, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, United States; 3Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States; 4Department of Pediatrics, Northwestern University, Chicago, IL, United States; 5Department of Cardiology, Ann & Robert H Lurie Childrens Hospital of Chicago, Chicago, IL, United States

The aim of the current study is to assess the impact of aortic coarctation on aortic 3D blood flow characteristics in a cohort of pediatric, young adult, and adult patients compared to a control group without coarctation, as matched for age, valve morphology and aortic diameter. Results demonstrate that the presence of coarctation or coarctation repair alters blood flow hemodynamics along the entire thoracic aorta. The coarctation group had significantly higher grade helical flow in all regions of the aorta, and the subgroup of non-repaired coarctation had higher grade helical flow than repaired coarctation.

Abstract PDF Poster PDF

Keywords

additionally adult advanced altered alters anatomy anterior aorta aortic apex approaches approved arch arrowhead ascending assessment attempt barker bicuspid biomedical blood body card cardiology cardiovascular caudal characteristics charts children clearly cohort comprised conditions contrast control controls correlation covering cranial create dedicated derangement descending diameter diameters directed disease diseased dissection downstream elasticity engineering enhanced entire evaluated excellence except exhibiting extent finally finding flow foundation general geometry grade graded gradings grants helical hospital illustrates inclusion increasing indexed individual initiative intrinsic larger local matched medicine minimal morphology northwestern note observers oliver patient patients pattern patterns peak pediatric pediatrics population posterior posteriorly presence previously profile program progression protocol quadrants radiology rank rather related repair repaired repairs represent representation resolution resolved risk root segments selected shear significantly software spatial subgroup subgroups subsequent suggests suited support surface surgical systems systolic table temporal thoracic translational ultimately undergone underwent uniformity valve velocity view visualization volume wall white years young