Meeting Banner
Abstract #1320

Minimizing Dark-Rim Artifacts in First-Pass Myocardial Perfusion MR by Eliminating Gibbs Ringing Using Projection Imaging

Behzad Sharif1, Rohan Dharmakumar1, Troy LaBounty1, Chrisandra Shufelt2, Louise EJ Thomson2, Noel Bairey Merz2, Daniel S. Berman2, Debiao Li1

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; 2Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

A major limitation for first-pass perfusion myocardial MRI is the presence of the so-called dark rim artifacts (DRAs), which may confound interpretation and diagnosis of subendocardial perfusion defects. A major cause of DRAs is known to be Gibbs ringing along the subendocardial border. In this work we demonstrate that projection imaging significantly reduces the prevalence and spatial extent of subendocardial DRAs in first-pass perfusion imaging, compared to conventional Cartesian techniques.

Keywords

absolute accelerated accuracy acquisition advanced alternatively angular arrows artifact artifacts assess assessment beats biomedical blinded border bottom built called capable caption cardiac cause cavity cedars clearly clinical clinically common confound consensus consider contrast correspond coverage dark defects deficits defined described details diagnosis domain early eliminating enables encodes enhancement even evident exhibits expert extent findings fixed flash frame functions gelatin healthy heart hence human improve inherent initial institute insufficient iterative known limitation local major matched maximal medical mild minimal minimizing minutes missing mistaken model myocardial noel ones outside panels parallel pass patterns perfusion phantom pixel prepared presence prevalence projection protocol pulse qualitative quality quantitative radial read readers readout readouts realistic reconstruction reduced reduces reducing relatively representative resolution respectively rest ringing robustness samples sampling scanner schematic scheme scores scoring sense series settings severe shot significantly space spatial spread streaking streaks studied studies subjects summary superiority theory trials troy verify verifying visually volunteers width