Meeting Banner
Abstract #1308

Phase Sensitive Dual Inversion Recovery for Accelerated Multi-Slice Carotid Vessel Wall Imaging

Gabriele Bonanno1, 2, David Brotman1, 2, Matthias Stuber1, 2

1Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL),, Lausanne, Vaud, Switzerland; 2Center for Biomedical Imaging (CIBM), Lausanne, Vaud, Switzerland

A novel extension of phase-sensitive dual inversion recovery (PS-DIR) is proposed, implemented and tested for carotid vessel wall imaging. By probing the statistical distribution of the phase image carotid lumens are automatically segmented and their residual signal suppressed. The proposed PS-DIR technique was tested in healthy adult subjects and provided effective blood-suppression over a broad range of inversion times enhancing lumen-to-vessel wall contrast and vessel wall sharpness in the carotid arteries. Preliminary results of a multi-slice implementation showed to improve volumetric coverage with a 3-fold acceleration in scanning time.

Abstract PDF Poster PDF

Keywords

accelerated acquisition addresses adult anatomical appears arrow artifact artifacts assigned audience axial bifurcations biomedical black blood bright broad bubble carotid carotids class clinical coil computed constant constraints contrast correct corrected cost coverage dark dashed dedicated depends distribution distributions drawn dual effective enabled enables enhances every example exploiting extension external extra extract findings fold free gradient healthy heart histogram hospital human implemented improved in vivo includes increment independent inefficient inside intensity internal inversion issues lead limits lumen magnitude makes mandatory materials matrix mixture model moreover noise novel nulling occurs opportunity optimal original paired performance pixels plot populations posterior preliminarily prior probability produces proposed pulse qualitative quantitative quantitatively radiology rather reconstruction recovery related remains removes representative residual resolution scanning segment segmentation segmented sensitive sharpness significantly since slice soap solid sons spatial starting statistical subject subjects successfully sufficient suppression surrounding system tailed target thresholded tissue tool translational triggered trio upper vessel volumetric volunteers wall whereas window