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Abstract #1292

Noncontrast-Enhanced Four-Dimensional MR Angiography at 7T

Gregory J. Metzger1, Sebastian Schmitter1, Xiufeng Li1, Pierre-Francois Van de Moortele1, Peter Schmitt2, Xiaoming Bi3

1Center for Magnetic Resonance Reserach, University of Minnesota, Minneapolis, MN, United States; 2MR Application & Workflow Development, Siemens AG, Erlangen, Germany; 3Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL, United States

Arterial spin labeled (ASL) 4D MRA has been shown to be a valuable method for simultaneously assessing anatomic structure and dynamic filling of cerebral arteries. Beyond improved SNR and parallel imaging performance, performing these studies at ultrahigh will improved visualization of distal vessels, especially in conditions of reduced flow, due to prolonged T1 relaxation times resulting in more persistent labeling. A dynamically applied transmit B1 (B1+) shimming strategy was employed to accommodate limitations on peak B1+, B1+ homogeneity and SAR. Initial results showing signal persistence in distal arteries are shown.

Keywords

achieved acquisition acquisitions address allowing amplifiers anatomic angiography application applied appreciated arterial arteries attempt background balanced blood blue body bolus brain calibration cardiovascular cerebral challenges coil conditions consisted constraints contraindications contrast control course decrease demonstrating described development dimensional distal dynamic dynamically efficiency efficient eliminates enhanced especially every excellent excitation field fields fitting flow foundation frame frames funding gradient hardware hashed head homogeneity immediately improve improved increasing initial intensity intervals inversion isotropic label labeled labeling last like location locations longer magnetization maintaining minutes mode moving necessary observing optimization optimize optimized partial performance persistence persistent pixel planning power preparation previously prior pulse pulses radiology rapidly readout readouts reasonable reduced relatively resolution resolved saturation scanner segmented sensible separate shim shimming simply slice solely solution solutions speed spin spins star static strategies strategy structure subtraction superior suppression surrounding targeting temporal thick transceiver transmit uniform upon vessel vessels visualization volume volumes volumetric wave weaker whole windowed