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Abstract #1132

A Simple and Effective Approach for Carotid Plaque Risk Assessment in Clinical Practice

XIN PU1, 2, Chun Yuan1, Hunter R. Underhill1, Zhan Ming Fan3

1Vascular Imaging Lab, Department of Radiology, University of Washington, Seattle, WA, United States; 2Department of Radiology , Beijing Anzhen Hospital, Capital Medical University, Beijing, China; 3Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China

It has been well known that intraplaque hemorrhage and fibrous cap rupture are the most critical features of carotid plaque instability. Carotid atherosclerotic score(CAS) was built to stratify the plaque severity.However,CAS assessment requires a relatively long time for the review process,which is limit the application in clinical practice. This study sought to find a simple, fast approach to evaluate the CAS and stratify the severity of carotid plaque in clinic.

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Keywords

able accurately agreement always analyzed analyzing application artery assess assessment assuming atherosclerosis automatic background boundaries calculation capability capital carotid china circumstance classifier clinic clinical components considered contrast critical currently define defined effective efficient enhanced extensively fast faster features fibrous fully generally good hemorrhage histological hospital human hunter hypothesis in vivo individuals instability kappa limited locations long lumen manual marina medical medicine ming modality morphology need noninvasive optimal outer plaque plaques potentially practice predict presence probabilistic process promising quantitatively radiology rather recruited relatively required requires resolution respectively reviewed reviewers risk rupture score segmentation several severity simple still stratify strong stronger subgroup subjects system takes tier tool totally validated vascular versus visualizing whole yuan