Meeting Banner
Abstract #1128

Assessment of Arterial Supply to Arteriovenous Malformations with Vessel-Encoded Arterial Spin Labeling Dynamic Angiography

Thomas W. Okell1, Meritxell Garcia2, Michael A. Chappell, 13, James V. Byrne4, Peter Jezzard1

1FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; 2Division of Diagnostic & Interventional Neuroradiology, Department of Radiology & Nuclear Medicine, University of Basel Hospital, Basel, Switzerland; 3IBME, Department of Engineering, University of Oxford, Oxford, United Kingdom; 4Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom

Arteriovenous malformations (AVMs) can be treated by endovascular embolization, but it is crucial to have knowledge of the arterial supply to the lesion prior to treatment. In this study we applied a 2D dynamic angiographic technique based on vessel-encoded pseudocontinuous arterial spin labeling (VEPCASL) to non-invasively visualize the flow patterns arising from the main feeding arteries to AVMs. Each transverse, coronal and sagittal time-resolved data set took about four minutes to acquire. Good image quality and vessel-selectivity was observed in all five patients. We hope this will become a useful tool for treatment planning in AVM patients.

Keywords

acceleration according acquisition affect allowing angiography anterior appears apply approval arrows arterial arteries artery assessment association blood blue brain branch branches cardiac carotid carry cerebral chosen circled clearly clinical closer coded coronal cover cyan cycles decoded demonstrating depiction determined diagnostic division drainage draining duration dynamic early encoded encodings engineering ethical example excellent extract feeding five flight flow fluid free funding good healthy hemispheres hope institutional intensity interfering invasive investigating kinetic kingdom labeling late legend lesion limited local locations mainly make male malformations measures medical medicine middle minor mixing modification motion needed novel nuclear oblique often orange oxford patient patients patterns perhaps peter planning posterior posteriori precession prevent radiology readout reduction resolution risks scalp scanned selected selection selective separate separation significantly slab spin steady stroke subject supplied supply supplying support surgery tagging temporal therapeutic therapy tool transverse triggering trust typically useful valuable veins venous vessel vessels visualized visualizing volunteers whilst window yellow