Meeting Banner
Abstract #1067

Erythropoietin (EPO) as Treatment of Mild Traumatic Brain Injury: A Multi Modal MRI Study

Kurt Hermann Bockhorst1, Robert Garcia2, Samson Kujit Gaddam2, Claudia S. Robertson2, Ponnada A. Narayana1

1DII, University of Texas, Houston, TX, United States; 2Neurosurgery, Baylor College of Medicine, Houston, TX, United States

mild traumatic brain injury (mTBI) affects millions of people each year. A treatment is unknown. He we present a potential therapeutic agent, eryrhropoietin, which has been shown to be beneficial in other brain injuries as TBI or global ischemia. We used MRI, especially DTI, to quantify the effects of erythropoietin on mTBI.

Keywords

absence acquisition acquisitions anatomical anatomy animals anti appears application available blood body brain breathing caps capsule caused choline college confirms consisted constantly contrast controlled contusion cortex cortical damage decreased described determined diffusivity disorders displayed divided double dual echoes edema effective eight elevated elsewhere emotional enhanced enlarged equilibrium exclusively experimental external feedback fixed general gradient graphs heads hemisphere icosahedral impact included indicate inflammatory injury integrity intracellular larger leakage long longitudinal loss maintained maintaining mask material measure measured mechanisms mediated medicine metrics micro middle mild million mixture modal modified monitored mouth natl navigator neural neurosurgery operated outcome oxygen possibly post press procedure promotes proves pulse rapid rare rats recent rectal related resolution resolved reveal saline sampling saturation scanned scheme sham significantly siren site sleep slices smaller software spatial spectroscopy structure structures studies subdivided suffer suggest supplied suppresses system tail temperature tissue tool traumatic treated treatment vascular velocity villa visualizing volume volumes warm weeks