Sanjay Kalra1,
Peter Seres1, Changho Choi2
1University
of Alberta, Edmonton, Alberta, Canada; 2University of Texas Southwestern
Medical Center, Dallas, TX, United States
Single voxel spectroscopy of glutamate and GABA was performed at 3T in the motor cortex in patients with ALS. Glutamate was decreased 13%. GABA was unchanged, however correlations with clinical indices were present for both glutamate and GABA.