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Abstract #0920

Altered Glutamatergic Metabolism Is Associated with Punctate White Matter Lesions in Preterm Infants

Jessica L. Wisnowski1, 2, Stefan Bluml1, Lisa Paquette3, Elizabeth Zelinski4, Marvin D. Nelson, Jr1, Michael J. Painter5, Hanna Damasio2, Floyd Gilles6, Ashok Panigrahy, 17

1Radiology, Children's Hospital Los Angeles, Los Angeles, CA, United States; 2Brain and Creativity Institute, University of Southern California, Los Angeles, CA, United States; 3Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, United States; 4Gerontology, University of Southern California, Los Angeles, CA, United States; 5Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States; 6Pathology, Children's Hospital Los Angeles, Los Angeles, CA, United States; 7Radiology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, United States

 

Keywords

abnormal abnormally absolute acquisition acute additional altered although among analyses approximately association audience available axial basis bilateral birth births brain cerebral children choline chronic circled clinical clinically completed concentration concentrations contemporaneously content contrast corrected creativity decreased defined differed diffusion disabilities distinguishing elevated epoch evidence evolving failure final findings five fluid fractions gerontology gestational glutamate head hemorrhage hospital hypothesis hypothesized included independently indicate indicated indications infant infants infection injury institute institution intensity internal lactate last lesions limits matrix measure mechanism mechanisms menstrual metabolism metabolite metabolites mild milliseconds model moderate monitoring morphology mother natal necessarily neonatal neonate neonates often outcome outlined overall parietal pathogenesis patient patterns pediatric pediatrics period placed plus predominant press processed prognostication protocol radiology relevant repetition represents respectively reviewed risk scale scanner scored severe significantly slice software southern spacing spectra spectroscopy spectrum standardized studies support sustained system target tertiary treatment trials tumor underlying useful varying ventricle vessel water weeks white