Meeting Banner
Abstract #0891

A Comprehensive Evaluation of Regional Cortical Thickness in a Large Cohort of Healthy Controls: Gender and Field Strength Dependence

Koushik A. Govindarajan1, Ponnada A. Narayana1

1Department of Diagnostic and Interventional Imaging, UT Health Science Center at Houston, Houston, TX, United States

Cortical thickness (Cth) provides crucial information about normal brain development. Measured Cth could depend on multiple factors such as gender, field strength and type of MRI scanner. The dependence of Cth on field strength has not been studied in a large sample size. Also, with the increased use of 3T scanners, evaluating the effect of higher field strength on Cth is critical. This study evaluates the effect that gender and field strength has on measured cortical thickness and its age-dependent changes in a large cohort of 300 healthy controls.

Abstract PDF

Keywords

accessed account affected affecting aging allows available best brain brains calculation cerebral cohort commonly comparable comprehensive consistent contrast controls cortex cortical critical crucial databases demographic depend dependence dependent determine development diagnostic disorders either ensure estimating estimation evaluated evaluation example extrinsic female females field find frontal fusiform gender global health healthy hemisphere ideally important improved in vivo indicate inferences inferior influenced interpretation intrinsic investigated investigating iterations knowledge larger lateral make male males maps matched measure measured might much need normally parietal pipeline plots pole pool posterior processed pronounced publicly published reason refer regional regression relatively reported robust sample scanner scanners science simulation strength structures studies subject summarized summary superior surfer table take temporal thicker transverse trends type valid various views whereas