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Abstract #0881

Time Resolved Coronary Vessel Wall MRI Using Phase-Sensitive DIR (TRAPD)

Khaled Z. Abd-Elmoniem1, Ahmed M. Gharib1, Roderic I. Pettigrew2

1National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, United States; 2National Institute of Biomedical Imaging and Bioengineering, NIH, Bethesda, MD, United States

Technical challenges still hinder coronary wall imaging for routine clinical utilization. The purpose of this study was to develop a time-resolved acquisition of phase-sensitive DIR (TRAPD) coronary vessel wall MRI that overcomes the loss of the orthogonality due to uncompensated residual motions

Keywords

ability accurate achieved acquisition addition adequate anatomic another arrow arrows arterial artery assessment automatically axis bioengineering biomedical black blood bulk capture challenges cine clinical consecutive consisted constant contrast contrasts coronary curves degradation denote develop deviation disease dotted enhanced example excitation extended fashioned fast five flow flowing frame frames great healthy heart hence hinder history implemented improve improved in vivo inclusive incremental inside institute interleaves interval inversion kidney least longitudinal loss lumen made magnetization magnitude many matrix measured modified modulus motion motions narrower national nulled occurs oftentimes optimal orthogonal orthogonality overcome overcomes patient patients period periods permit perpendicular phantom plastic populations position precision preparation preserved preventive pulse quality quantitative radiology readout reconstructed recovery residual resolution resolved rest restored risk segment selective sensitive series several sign signed slice slices spatial spiral statistically stay still strain subject subjects suboptimal subsequent substantially success successfully successive technical temporal thinnest tissue tube uncompensated utilization validated vary vessel wall window