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Abstract #0877

Validation of 3D Multi-Contrast Black Blood Sequences with Large Coverage for One-Stop Neurovascular Screening

Zechen Zhou1, Rui Li1, Xihai Zhao1, Le He1, Chun Yuan, 12

1Department of Biomedical Engineering, Tsinghua University, Beijing, China; 2Department of Radiology, University of Washington (Seattle), Seattle, WA, United States

Multi-contrast Black Blood (BB) MRI can effectively detect and measure the atherosclerotic plaque morphology and components. Currently wide used 2D T1W and T2W BB imaging sequences might give rise to missed or false diagnosis due to the limitations of the lesion detection range and partial volume effect. In this study, we suppose to apply the recently proposed 3D multi-contrast BB techniques including MERGE, VISTA and SNAP to cover the major intracranial and entire extracranial arteries and we found that the blood suppression effectiveness and image quality for diagnosis in this large-coverage situation can fully support for the one-stop neurovascular screening.

Keywords

acquisition application applications appropriately arisen around arteries artery artifacts association augmented background basically bear beds besides better bifurcation biomedical black blood burden carotid channel china clinical coil components consider contaminated contrast coronal correlated cost cover coverage currently curve dedicated degree depend dependent detect detected detection diagnose diagnosis diagnostic distributed distribution effective effectiveness either enlarge entire especially experienced exploits flow flowing fully give grades gradient highly illustrated included indicate investigated isotropic lesion limited long lumen major measure measured merge middle might missed module morphology much nearly optimized others outperforms overcome page partial particular patients performance plaque plaques preserve primary principles qualitative qualities quality quantitative radiology readout reconstruction reduction regarded relatively resolution score screening segment segments selection several similarly simply since slab snap spatial statistically stop stroke sufficient superior suppose suppress suppressed suppression system table takes terms tool traditional understanding validation variable vascular vessel violated vista visualized void volume wall whole whose yuan