1Department
of Biomedical Engineering, Tsinghua University, Beijing, China; 2Department
of Radiology, University of Washington (Seattle), Seattle, WA, United States
Multi-contrast Black Blood (BB) MRI can effectively detect and measure the atherosclerotic plaque morphology and components. Currently wide used 2D T1W and T2W BB imaging sequences might give rise to missed or false diagnosis due to the limitations of the lesion detection range and partial volume effect. In this study, we suppose to apply the recently proposed 3D multi-contrast BB techniques including MERGE, VISTA and SNAP to cover the major intracranial and entire extracranial arteries and we found that the blood suppression effectiveness and image quality for diagnosis in this large-coverage situation can fully support for the one-stop neurovascular screening.