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Abstract #0857

Two-Dimensional J-Resolved LASER Spectroscopy of Human Brain at 3T

Meijin Lin1, Anand Kumar1, Shaolin Yang1, 2

1Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States; 2Department of Radiology, University of Illinois at Chicago, Chicago, IL, United States

In this report, two-dimensional (2D) J-resolved spectroscopy using localization by adiabatic selective refocusing (LASER), named as J-resolved LASER, was introduced to suppress the chemical shift artifacts, additional J-refocused artifactual peaks resulted from spatially dependent J-coupling evolution, and the sensitivity to radiofrequency field inhomogeneity. Phantom and human experiments were performed to demonstrate the feasibility and advantages of J-resolved LASER spectroscopy over conventional J-resolved spectroscopy (JPRESS).

Keywords

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