Measurement of Absolute CMRO2 by Simultaneous Hypercapnic and Hyperoxic Calibration of fMRI Signal

Keywords

absolute acquisition administered administration advantage alternative although anatomical appears applied assume assumptions audience begun bold boundary brain calculation calibrated calibration cerebral challenges clinicians combined combines concentration concentrations conditions consistent density design dual dynamic efficient eleven emerge excite excluded expand experimental exponent expressed extract extraction female fewer forcing fraction framework frontal functions gradient induce induced inspired integration inter intermittent kingdom literature matrix measure metabolism model moreover need needed observations occipital often oxygen paradigms parietal partial permitting physiological potential pressures previous priors probability proximal psychology quantify quantitative quoted readout reduces regional relates relating replace reported reports researchers respectively respiratory rest scanned school sensitivity sequential shorter simultaneous since slice slices slightly spatially spiral stone stroke subjects system target targeted thalamus tidal typically uniform variables vascular venous volumes wise years yield