Free-Water Elimination for Assessing Microstructural Gray Matter Pathology - With Application to Alzheimer's Disease

Keywords

acquisition adds advantageous affine agreed alterations altered although anisotropy applied applying assessed assumes assumption atrophic atrophy beyond biological broad cancer caused cells cellular challenging characterization compartment compartments complexity computer computing confounding consistently controls corrected correlated correlation cylindrically datasets decreased density depth derived differentiation difficult diffusion directly discrepancy disease dispersion distinguish division elimination estimation even explained explains extra extracellular fact finding findings fraction fractional fractions free furthermore gray head healthy highly hindered implies informatics interestingly interpret intra isotropic macroscopic major malformation material measure measuring medical methodologies microscopic misclassified model modeled modeling models motion needed needs negative offers optimal optimized organization orientation originally part partial pathology patients prescribes previously protocol psychiatry quantitative quantitatively recent referred registered relevance remaining repetitions reported richer risk robustly schematically scheme school science seemingly separate serve shell shells significantly space special statistical sticks strong structural subjects suggests surrounding technical tensor tensors tissue transformation types underlying volume water whereas white