Xin Li1,
Jeffrey M. Njus1, Seymur Gahramanov2, Csanad G.
Vrallyay2, John W. Grinstead3, Charles S. Springer,
Jr. 1, Edward A. Neuwelt2, William D. Rooney1
1Advanced
Imaging Research Center, Oregon Health & Science University, Portland,
OR, United States; 2Department of Neurology, Oregon Health &
Science University, Portland, OR, United States; 3Siemens
Healthcare, Portland, OR, United States
For DCE-MRI, it is possible to obtain consistent Ktrans (CR transfer constant) and ve (extracellular, extravascular volume fraction) values whether incorporating vb (blood volume fraction) or not into DCE-MRI modeling. This often requires minimizing the influence of vb in DCE-MRI data time-courses.