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Abstract #0687

Quantitative 23Na MRI of Human Knee Cartilage Using Dual-Tuned 1H/23Na Transceiver Array RF Coil at 7T

Chan Hong Moon1, Jung-Hwan Kim1, Tiejun Zhao2, Kyongtae Ty Bae1

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2MR R&D Collaborations, Siemens Healthcare, Pittsburgh, PA, United States

We developed a new high-sensitivity multi-channel 23Na RF coil for knee MRI at 7T. Our 1H/23Na MRI allowed quantitative measurement of [23Na] in knee cartilage by taking into consideration of the 23Na imaging point spread function and 1H imaging cartilage thickness.

Keywords

acceptable accurate accurately addition adds anatomy anterior applications applied approved array arrowheads articular artifacts biochemical birdcage board boundary cartilage cartilages channel channels characteristics clinical coil coils combining concentration considered considering contour corrected correction criteria criterion curve cylindrical decay decrease decreased design developed dimension disease dotted double dual equation evaluate fast femoral field filtering fitting frame full function grant green hong human improve indicate inhomogeneity institutional intensity investigate investigated isotropic knee limit linearly loops magnitude major maps marker materials measured medical millimeter moon morphological osteoarthritis overlapping panels part partial particularly patients perimeter pixel placed potential potentially profile profiles proposed quantification quantified quantitative radial radiology reception reconstruct relationship repositioning resolution review scanner scholar sensitivity series setup seven significance simulated simulation sinusoidal soft solutions spatial specimen spine spiral spread statistical steady subject subjects summed supported systematically technology thereby thin tissues transceiver transmission tuned ultra understanding variation variations varied varying vector volume white width worthwhile