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Abstract #0685

Technical Feasibility of Two-Component T2* Mapping on Cartilages in Human Knee with 54-TE Acquisitions

Yongxian Qian1, Jinbai Huang1, Vincent K. Lee1, Fernando Emilio Boada2

1Radiology, University of Pittsburgh, Pittsburgh, PA, United States; 2Radiology, New York University, New York, NY, United States

A major challenge to two-component T2* mapping on cartilages in human knee at pixel level is the instability of mapping for the short-T2* component due to insufficient signal-to-noise ratio (SNR) available in clinical setting. A large number of TE acquisitions was proposed in this work to mitigate the demanding of high SNR and stabilize the mapping of short-T2* relaxation. The technical feasibility of this idea was successfully tested in this study.

Keywords

acquiring acquisition acquisitions adult allow approved articular automatic available averaging basis capability cartilage cartilages cell challenging channel clearly clinical coil collagen color complete component consistent curve customer deep detect developed developing deviation disruption disruptions early error excitation feasibility feasible femoral fiber fibers fitting fraction healthy human illustrates improve individual intensity iterative knee lateral layers limited location locations long mapping maps mater matrix measured medial medical modified noise optimizing organized osteoarthritis performance pixel pixels potential produced proposed protocol pulse quantification radiology readout required resolution runs scanned scanner separating setting short shortened sign slices solutions spiral spirals still subject subjects superficial technical technically tibial trio ultrashort variations view visible